Product Name: HSD11B2 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: HSD11B2 antibody can be used for detection of HSD11B2 by ELISA at 1:62500. HSD11B2 antibody can be used for detection of HSD11B2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 45 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD11B2.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1861-32-1
Product: EAI045
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store HSD11B2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HSD11B2, AME, AME1, HSD11K, HSD2, SDR9C3
Accession NO.: NP_000187
Protein Ino: 119392083
Official Symbol: HSD11B2
Geneid: 3291
Background: HSD11B2 catalyzes the conversion of cortisol to the inactive metabolite cortisone. It modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
PubMed ID:http://aac.asm.org/content/24/1/42.abstract
