Product Name: Histone Deacetylase 1 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC, WB
Applications: Histone Deacetylase 1 antibody can be used in Western Blot, and immunohistochemistry starting at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Amino acids 466-482 of Human HDAC-1
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 67330-25-0
Product: PF06650833
Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Concentration:
Storage Conditions: Store Histone Deacetylase 1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HDAC1, Histone deacetylase 1, GON-10, HD1, RPD3, RPD3L1
Accession NO.: Q13547
Protein Ino: 2498443
Official Symbol: HDAC1
Geneid: 3065
Background: HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
PubMed ID:http://aac.asm.org/content/22/5/824.abstract
