Product Name: HIP2 Antibody
Species Reactivity: Dog, Human, Mouse, Rat, Zebrafish
Tested Applications: ELISA, WB
Applications: HIP2 antibody can be used for detection of HIP2 by ELISA at 1:312500. HIP2 antibody can be used for detection of HIP2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 22 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HIP2.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 209342-40-5
Product: IDE1
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store HIP2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HIP2, HYPG, LIG, UBE2K, HIP2, UBC1, E2-25K
Accession NO.: NP_005330
Protein Ino: 4885417
Official Symbol: UBE2K
Geneid: 3093
Background: HIP2 belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. It binds selectively to a large region at the N terminus of huntingtin. This interaction is not influenced by the length of the huntingtin polyglutamine tract. This protein has been implicated in the degradation of huntingtin and suppression of apoptosis.
PubMed ID:http://aac.asm.org/content/22/4/652.abstract
