Product Name: HIF1A Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 93 kDa
Immunogen: This HIF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 735-762 amino acids from the C-terminal region of human HIF1A.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1354825-62-9
Product: AMG 487 (S-enantiomer)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.49 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Hypoxia-inducible factor 1-alpha, HIF-1-alpha, HIF1-alpha, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78, bHLHe78, Member of PAS protein 1, PAS domain-containing protein 8, HIF1A, BHLHE78, MOP1, PASD8
Accession NO.: Q16665
Protein Ino: 2498017
Official Symbol: HIF1A
Geneid: 3091
Background: Hypoxia-inducible factor-1 (HIF1) is a transcriptionfactor found in mammalian cells cultured under reduced oxygentension that plays an essential role in cellular and systemichomeostatic responses to hypoxia. HIF1 is a heterodimer composed ofan alpha subunit and a beta subunit. The beta subunit has beenidentified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1.Overexpression of a natural antisense transcript (aHIF) of thisgene has been shown to be associated with nonpapillary renalcarcinomas. Two alternative transcripts encoding different isoformshave been identified.
PubMed ID:http://aac.asm.org/content/22/4/560.abstract
