Product Name: Hexokinase 1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: Hexokinase 1 antibody can be used for detection of Hexokinase 1 by Western blot at 1 – 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 101 kDa Observed: 103 kDa
Immunogen: Hexokinase 1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Hexokinase 1.The immunogen is located within amino acids 830 – 880 of Hexokinase 1.
Host Species: Rabbit
Purification: Hexokinase 1 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 529-53-3
Product: Saroglitazar
Buffer: Hexokinase 1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: Hexokinase 1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HK, HXK
Accession NO.: NP_000179
Protein Ino: 188497754
Official Symbol: HK1
Geneid: 3098
Background: There are four major glucose-phosphorylating isoenzymes, designated Hexokinase 1 I, II, III, and IV (1). Hexokinase 1 activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway (1,2). Hexokinase 1 2 is the predominant Hexokinase 1 isozyme expressed in insulin-responsive tissues such as skeletal muscle and its expression is insulin-responsive (3). It is involved in the increased rate of glycolysis seen in rapidly growing cancer cells (4).
PubMed ID:http://aac.asm.org/content/22/3/426.abstract
