Product Name: HDAC8 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, WB
Applications: HDAC8 antibody can be used for detection of HDAC8 by ELISA at 1:1562500. HDAC8 antibody can be used for detection of HDAC8 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 42 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HDAC8.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 372523-75-6
Product: N-(5-Aminopentyl)acetamide
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store HDAC8 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HDAC8, HDACL1, RPD3, HD8, WTS, CDA07, CDLS5, MRXS6
Accession NO.: NP_060956
Protein Ino: 8923769
Official Symbol: HDAC8
Geneid: 55869
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
PubMed ID:http://aac.asm.org/content/21/4/666.abstract
