Product Name: hCG Receptor / LH Receptor Antibody [LHCGR/1415]
Species Reactivity: Human
Tested Applications: Flow, IF, WB
Applications: Flow Cytometry: 0.5-1 ug/million cells in 0.1mlIF: 1-2 ug/mlWB: 0.5-1 ug/mlOptimal dilution of the hCG Receptor antibody should be determined by the researcher.
User Note: Optimal dilutions for each application to be determined by the researcher
Predicted Molecular Weight:
Immunogen: A partial recombinant protein from the N-terminal region of human Luteinizing hormone / Choriogonadotropin receptor was used as the immunogen for the hCG Receptor antibody.
Host Species: Mouse
Purification: Protein G affinity chromatography
Physical State: Liquid
CAS NO.: 2479-49-4
Product: Coenzyme Q9
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Conditions: Aliquot and Store at -20C. Avoid freez-thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: LHCGR, luteinizing hormone/choriogonadotropin receptor, LCGR, LGR2, LHR, hLHR, luteinizing hormone receptor, lutropin/choriogonadotropin receptor, LH receptor, CG receptor, LHRHR
Accession NO.:
Protein Ino:
Official Symbol: LHCGR
Geneid: 3973
Background: Recognizes a protein of 78-85kDa, which is identified as the receptor for Luteinizing hormone / Choriogonadotropin. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
PubMed ID:http://aac.asm.org/content/21/3/421.abstract
