Share this post on:

Product Name: HAVCR1 Antibody
Species Reactivity: Human, Mouse
Tested Applications: IHC, WB
Applications: HAVCR1 antibody can be used in immunohistochemistry starting at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: HAVCR1 antibody was raised against amino acids 200 – 300 of HAVCR1 (Human).
Host Species: Rabbit
Purification: Protein G Column
Physical State: Liquid
CAS NO.: 1001288-58-9
Product: PD-1-IN-1
Buffer: PBS, 0.05% sodium azide.
Concentration: 1 mg/ml
Storage Conditions: Store HAVCR1 antibody at 4 ˚C for short term applications. For long term storage, aliquot and -20 ˚C.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HAVCR1, HAVCR-1, KIM-1, Kidney injury molecule 1, KIM1, T-cell membrane protein 1, TIM1, TIMD1, TIM-1, HAVCR, TIMD-1
Accession NO.: Q96D42
Protein Ino: 73919877
Official Symbol: HAVCR1
Geneid: 26762
Background: HAVCR1, a 359 A.A Class 1 integral membrane glycoprotein, is used by Hepatitis A virus to infect humans. It consists of a conserved N-terminal Cys-rich region, IgV (Immunoglobulin Variable region like) domain and a TSP-rich mucin domain in the extracellular region followed by a highly conserved tyrosine kinase phosphorylation motif in the cytoplasmic region. HAVCR1 is expressed on terminally differentiated CD4+ Th2 cells and regulates cytokine production. It plays an important role in the regulation of immune responses in the development of asthma and allergic responses. Its expression is critically upregulated in dedifferentiated kidney cells, thus indicating a possible role in regeneration of proximal tubule epithelium in Kidneys. HAVCR1 has shown to be upregulated in renal carcinomas, suggesting its role in tumor progression and metastasis.
PubMed ID:http://aac.asm.org/content/21/2/294.abstract

Share this post on:

Author: Betaine hydrochloride