Product Name: HAL Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: HAL antibody can be used for detection of HAL by ELISA at 1:1562500. HAL antibody can be used for detection of HAL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 72 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HAL.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 114828-90-9
Product: IT1t
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store HAL antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HAL, HIS, HSTD, histidase
Accession NO.: NP_002099
Protein Ino: 4504333
Official Symbol: HAL
Geneid: 3034
Background: HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.
PubMed ID:http://aac.asm.org/content/21/1/166.abstract
