Product Name: H2AFZ Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 14 kDa
Immunogen: This H2AFZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human H2AFZ.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1581270-11-2
P 22077
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Histone H2AZ, H2A/z, H2AFZ, H2AZ
Accession NO.: P0C0S5
Protein Ino: 83288408
Official Symbol: H2AFZ
Geneid: 3015
Background: Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Nucleosomes consist of approximately 146 bp of DNAwrapped around a histone octamer composed of pairs of each of thefour core histones (H2A, H2B, H3, and H4). The chromatin fiber isfurther compacted through the interaction of a linker histone, H1,with the DNA between the nucleosomes to form higher order chromatinstructures. This gene encodes a replication-independent member ofthe histone H2A family that is distinct from other members of thefamily. Studies in mice have shown that this particular histone isrequired for embryonic development and indicate that lack offunctional histone H2A leads to embryonic lethality. [provided byRefSeq].
PubMed ID:http://aac.asm.org/content/21/1/62.abstract
