Product Name: GYS1 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC, IP, WB
Applications: GYS1 antibody can be used in ELISA, and immunohistochemistry starting at 16 – 24 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: GYS1 antibody was raised against amino acids 249 – 265 of GYS1 (Human).
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 86784-80-7
L67
Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Concentration:
Storage Conditions: Store GYS1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: GYS1, Glycogen synthase 1 (muscle), GSY, GYS
Accession NO.: P13807
Protein Ino: 1351366
Official Symbol: GYS1
Geneid: 2997
Background: Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units. Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000. GS is subject to regulation through both allosteric and covalent modification and occurs in two forms: the phosphorylated inactive form, and the dephos-phorylated active form. GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3b that mainly functions to phos-phorylate muscle glycogen synthase. This antibody is specific for the phosphorylated form of GS at S640. Phosphorylation of GS at S640 has been associated with Antiphospholipid Antibody Syndrome.
PubMed ID:http://aac.asm.org/content/20/6/841.abstract
