Product Name: GTPase Activating Protein (phospho Ser387) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Western Blot: 1:500~1:1000
User Note:
Predicted Molecular Weight: 72 kDa
Immunogen: GTPase Activating Protein (phospho Ser387) antibody was raised against a peptide sequence around phosphorylation site of serine 387 (R-I-S (p)-G-C) derived from Human GTPase Activating Protein.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 480-19-3
HBX 19818
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: GTPase activating protein, GTPase activating protein ID-GAP, RAC GTPase- activating protein 1, RACGAP1, RAC GTPase-activating protein
Accession NO.: NP_001119575.1
Protein Ino: 21361397
Official Symbol: RACGAP1
Geneid: 29127
Background: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation.
PubMed ID:http://aac.asm.org/content/20/5/567.abstract
