Product Name: GTF2I Antibody
Species Reactivity:
Tested Applications:
Applications: GTF2I antibody can be used for detection of GTF2I by ELISA at 1:312500. GTF2I antibody can be used for detection of GTF2I by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 112 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTF2I.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 293754-55-9
(3R,4S)-Tofacitinib
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store GTF2I antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: GTF2I, BAP-135, BAP135, BTKAP1, DIWS, IB291, SPIN, TFII-I, WBS, WBSCR6, GTFII-I
Accession NO.: NP_127492
Protein Ino: 14670350
Official Symbol: GTF2I
Geneid: 2969
Background: GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon (s) encoding 5 UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants. This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Four transcript variants encoding different isoforms have been found for this gene.
PubMed ID:http://aac.asm.org/content/20/5/660.abstract
