Product Name: GSN Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: GSN antibody can be used for detection of GSN by ELISA at 1:62500. GSN antibody can be used for detection of GSN by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 83 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GSN.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 29106-49-8
ABT-737
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store GSN antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: GSN, DKFZp313L0718, ADF, AGEL
Accession NO.: NP_000168
Protein Ino: 4504165
Official Symbol: GSN
Geneid: 2934
Background: GSN binds to the plus ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the plus ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
PubMed ID:http://aac.asm.org/content/20/4/433.abstract
