Product Name: GSK3beta (phospho Ser9) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: IF, IHC, WB
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
User Note:
Predicted Molecular Weight: 46 kDa
Immunogen: GSK3beta (Phospho-Ser9) antibody was raised against a peptide sequence around phosphorylation site of serine 9 (T-T-S (p) -F-A) derived from Human GSK3β.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Physical State: Liquid
CAS NO.: 899713-86-1
Exherin (trifluoroacetate)
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: NFKB3, Factor A, GSK-3 beta, Protein kinase GSK-3-beta, kinase GSK-3 beta
Accession NO.: NP_001139628.1
Protein Ino: 225903437
Official Symbol: GSK3B
Geneid: 2932
Background: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin.
PubMed ID:http://aac.asm.org/content/20/3/410.abstract
