Product Name: GRPEL2 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: GRPEL2 antibody can be used for detection of GRPEL2 by ELISA at 1:312500. GRPEL2 antibody can be used for detection of GRPEL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 25 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GRPEL2.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 157654-67-6
AM095 (free acid)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store GRPEL2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: GRPEL2, DKFZp451C205, FLJ23713, FLJ33918, Mt-GrpE#2
Accession NO.: NP_689620
Protein Ino: 40255109
Official Symbol: GRPEL2
Geneid: 134266
Background: GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
PubMed ID:http://aac.asm.org/content/20/2/272.abstract
