Product Name: CD8B1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 24 kDa
Immunogen: This CD8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-167 amino acids from the C-terminal region of human CD8B1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 312917-14-9
Product: TCS JNK 5a
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: T-cell surface glycoprotein CD8 beta chain, CD8b, CD8B, CD8B1
Accession NO.: P10966
Protein Ino: 116032
Official Symbol: CD8B
Geneid: 926
Background: The CD8 antigen is a cell surface glycoprotein found onmost cytotoxic T lymphocytes that mediates efficient cell-cellinteractions within the immune system. The CD8 antigen, acting as acoreceptor, and the T-cell receptor on the T lymphocyte recognizeantigens displayed by an antigen presenting cell (APC) in thecontext of class I MHC molecules. The functional coreceptor iseither a homodimer composed of two alpha chains, or a heterodimercomposed of one alpha and one beta chain. Both alpha and betachains share significant homology to immunoglobulin variable lightchains. This gene encodes the CD8 beta chain isoforms. Multiplealternatively spliced transcript variants encoding distinctmembrane associated or secreted isoforms have been described. Apseudogene, also located on chromosome 2, has been identified.
PubMed ID:http://aac.asm.org/content/35/6/1108.abstract
