Product Name: CD4 Antibody [RPA-T4] (PerCP-Cy5.5)
Species Reactivity: Human
Tested Applications: Flow
Applications:
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen:
Host Species: Mouse
Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Physical State: liquid
CAS NO.: 83777-30-4
Product: DAOS
Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration: 5 uL (0.125 ug) / test
Storage Conditions: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.
Clonality: Monoclonal
Conjugate: PerCP-Cy5.5
Alternate Names: CD4mut, CD4
Accession NO.:
Protein Ino:
Official Symbol: CD4
Geneid: 920
Background: The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.
PubMed ID:http://aac.asm.org/content/34/9/1780.abstract
