Product Name: BRCA1 Antibody
Species Reactivity: Human
Tested Applications: IHC
Applications: BRCA1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: BRCA1 antibody was raised against amino acids surrounding Serine 1423 of BRCA1 (Human).
Host Species: Rabbit
Purification: Immunoaffinity Chromatography
Physical State: Liquid
CAS NO.: 140-87-4
Product: Cyanoacetohydrazide
Buffer: PBS, 0.02% sodium azide, 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: BRCA1 antibody should be stored long term (months) at -80 ˚C and short term (days) at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BRCA1, BROVCA1, BRCC1, Breast cancer 1, early onset, PPP1R53, PSCP, PNCA4, RING finger protein 53, RNF53, BRCAI, Breast cancer 1 early onset, IRIS
Accession NO.: P38398
Protein Ino: 728984
Official Symbol: BRCA1
Geneid: 672
Background: Associated with several familial cancers, including breast cancer, ovarian cancer, and prostate cancer. The cumulative lifetime risk of breast cancer for women who carry mutations in BRCA1 is approximately 92%, while the cumulative lifetime risk for noncarriers is estimated to be 10%. BRCA1 and BRCA2 participate together in a pathway (or pathways) associated with the activation of double-strand break repair and/or homologous recombination.
PubMed ID:http://aac.asm.org/content/42/5/1083.abstract
