Product Name: BPGM Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:2000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 30 kDa
Immunogen: This BPGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the C-terminal region of human BPGM.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 6700-34-1
Product: Dextromethorphan (hydrobromide hydrate)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Bisphosphoglycerate mutase, BPGM,3-bisphosphoglycerate mutase, erythrocyte,3-bisphosphoglycerate synthase,3-diphosphoglycerate mutase, DPGM, BPG-dependent PGAM, BPGM
Accession NO.: P07738
Protein Ino: 130350
Official Symbol: BPGM
Geneid: 669
Background: 2,3-diphosphoglycerate (2,3-DPG) is a small molecule foundat high concentrations in red blood cells where it binds to anddecreases the oxygen affinity of hemoglobin. This gene encodes amultifunctional enzyme that catalyzes 2,3-DPG synthesis via itssynthetase activity, and 2,3-DPG degradation via its phosphataseactivity. The enzyme also has phosphoglycerate phosphomutaseactivity. Deficiency of this enzyme increases the affinity of cellsfor oxygen. Mutations in this gene result in hemolytic anemia.Multiple alternatively spliced variants, encoding the same protein,have been identified.
PubMed ID:http://aac.asm.org/content/42/4/916.abstract
