Product Name: Betatrophin Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IHC-P, WB
Applications: Betatrophin antibody can be used for detection of Betatrophin by Western blot at 1 – 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 22 kDa Observed: 22 kDa
Immunogen: Betatrophin antibody was raised against a 16 amino acid peptide near the amino terminus of human Betatrophin.The immunogen is located within amino acids 40 – 90 of Betatrophin.
Host Species: Rabbit
Purification: Betatrophin antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 2398-81-4
Product: Nicotinic acid N-oxide
Buffer: Betatrophin antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: Betatrophin antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Betatrophin Antibody: RIFL, TD26, ANGPTL8, PRO1185, PVPA599, Angptl8, UNQ599/PRO1185, Betatrophin, Angiopoietin-like protein 8
Accession NO.: NP_061157
Protein Ino: 291219911
Official Symbol: C19orf80
Geneid: 55908
Background: The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels (1,2). Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis (3).
PubMed ID:http://aac.asm.org/content/42/2/369.abstract
