Product Name: Beta Catenin Antibody [12F7]
Species Reactivity: Human, Mouse, Rat
Tested Applications: Flow, IF, WB
Applications: Flow Cytometry: 0.5-1 ug/million cells in 0.1mlImmunofluorescence: 1-2 ug/mlWB: 1-2 ug/mlTitration of the Beta Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
User Note: Optimal dilutions for each application to be determined by the researcher
Predicted Molecular Weight:
Immunogen: A recombinant fusion protein consisting of the N-terminal half of human beta-Catenin fused to maltose binding protein was used as the immunogen for the Beta Catenin antibody.
Host Species: Mouse
Purification: Protein G affinity chromatography
Physical State: Liquid
CAS NO.: 1077-28-7
Product: α-Lipoic Acid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Conditions: Aliquot and Store at -20C. Avoid freez-thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: Catenin beta-1, Beta-catenin, CTNNB1, CTNNB
Accession NO.:
Protein Ino:
Official Symbol: CTNNB1
Geneid: 1499
Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]
PubMed ID:http://aac.asm.org/content/42/1/88.abstract
