Product Name: Bcl-xL Antibody
Species Reactivity:
Tested Applications:
Applications: Bcl-xL antibody can be used for detection of Bcl-xL by Western blot at 1 to 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Bcl-xL antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human Bcl-xL.The immunogen is located within the last 50 amino acids of Bcl-xL.
Host Species: Rabbit
Purification: Bcl-xL Antibody is Bcl-xL is supplied as ion exchange chromatography purified IgG.ide. .
Physical State: Liquid
CAS NO.: 4093-35-0
Product: Bromopride
Buffer: Bcl-xL Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: Bcl-xL antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Bcl-xL Antibody: BCLX, BCL2L, BCLXL, BCLXS, Bcl-X, bcl-xL, bcl-xS, PPP1R52, BCL-XL/S, BCLX, Bcl-2-like protein 1, Apoptosis regulator Bcl-X, Bcl2-L-1
Accession NO.: CAA80661
Protein Ino: 510901
Official Symbol: BCL2L1
Geneid: 598
Background: Bcl-xL Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-xL is a member of the Bcl-2 family of proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-xL is an anti-apoptotic mitochondrial protein related to Bcl-w and the major transcript of the bcl-x gene. Its high expression in tumors is correlated with advanced disease and poor prognosis. Bcl-xL expression level increases in response to several stimuli such as ionizing radiation and treatment with chemotherapeutic agents.
PubMed ID:http://aac.asm.org/content/53/12/5245.abstract
