Product Name: BCL 2 (Ab 70) Antibody
Species Reactivity: Human
Tested Applications: IF, IHC, WB
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
User Note:
Predicted Molecular Weight: 26 kDa
Immunogen: BCL-2 (Ab-70) antibody was raised against a peptide sequence around aa.68~72 (R-T-S-P-L) derived from Human BCL-2.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 532-11-6
Product: Anethole (trithione)
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Bcl-2, PPP1R50, PKR, PRKR, BCL2
Accession NO.: NP_000624.2
Protein Ino: 72198189
Official Symbol: BCL2
Geneid: 596
Background: BCL-2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
PubMed ID:http://aac.asm.org/content/53/11/4762.abstract
