Product Name: BCDIN3D Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000-2000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 33 kDa
Immunogen: This BCDIN3D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 243-276 amino acids from human BCDIN3D.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 6004-24-6
Product: Cetylpyridinium (chloride monohydrate)
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Pre-miRNA 5-monophosphate methyltransferase, 2.1.1.-, BCDIN3 domain-containing protein, BCDIN3D
Accession NO.: Q7Z5W3
Protein Ino: 74738762
Official Symbol: BCDIN3D
Geneid: 144233
Background: O-methyltransferase that specifically dimethylates the 5 monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5 monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre- miRNAs.
PubMed ID:http://aac.asm.org/content/53/11/4749.abstract
