Product Name: BANF1 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, IF, WB
Applications: BANF1 antibody can be used for detection of BANF1 by Western blot at 0.5 – 1 μg/mL. Despite its predicted molecular weight, BANF1 often migrates at a higher size in SDS-PAGE. Antibody can also be used for immunoflourescence starting at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: BANF1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BANF1.The immunogen is located within the last 50 amino acids of BANF1.
Host Species: Rabbit
Purification: BANF1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 333-41-5
Product: Diazinon
Buffer: BANF1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: BANF1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BANF1 Antibody: BAF, NGPS, BCRP1, D14S1460, BAF, BCRG1, Barrier-to-autointegration factor, Breakpoint cluster region protein 1
Accession NO.: AAH05942
Protein Ino: 13543577
Official Symbol: BANF1
Geneid: 8815
Background: BANF1 Antibody: Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA.
PubMed ID:http://aac.asm.org/content/53/10/4127.abstract
