Product Name: B2M Antibody [B2M-01]
Species Reactivity: Human
Tested Applications: ELISA, Flow, IHC, IP, RIA, WB
Applications: ELISA, FACS (1 ug/ml), ICC, IHC-P (10 ug/ml), Inhb, IP, RIA, WB (2 – 4 ug/ml)
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: B2M monoclonal antibody was raised against purified B2M (Human).
Host Species: Mouse
Purification: Ion Exchange Chromatography
Physical State: Liquid
CAS NO.: 94-20-2
Product: Chlorpropamide
Buffer: PBS, 15 mM sodium azide, approx., pH 7.4.
Concentration:
Storage Conditions: B2M antibody can be stored short term 4 ˚C. For long term storage aliquot and store at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: B2M, Beta 2 Microglobulin, Beta-2-microglobulin, Beta-2-microglobin
Accession NO.: P61769
Protein Ino: 48428791
Official Symbol: B2M
Geneid: 567
Background: beta2M is a 12 kDa Ig like glycoprotein expressed on lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells and epithelial cells. It is absent on erythrocytes. Beta 2-microglobulin is the low molecular weight component of HLA antigens and as such is involved in the presentation of endogenous antigens, activation of T lymphocytes and functional emergence of natural killer cells. It is found in the serum of normal individuals and in the urine in elevated amounts in patients with Wilson disease, cadmium poisoning and other conditions leading renal tubular dysfunction. ESTs have been isolated from libraries generated using virtually every tissue in the body.
PubMed ID:http://aac.asm.org/content/53/9/4015.abstract
