Product Name: AVP Antibody
Species Reactivity: Human
Tested Applications: IF, IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:50~100For IF starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 17 kDa
Immunogen: This AVP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-129 amino acids from the Central region of human AVP.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 84783-01-7
Product: K-Ras-IN-1
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Vasopressin-neurophysin 2-copeptin, AVP-NPII, Arg-vasopressin, Arginine-vasopressin, Neurophysin 2, Neurophysin-II, Copeptin, AVP, ARVP, VP
Accession NO.: P01185
Protein Ino: 128083
Official Symbol: AVP
Geneid: 551
Background: This gene encodes a precursor protein consisting ofarginine vasopressin and two associated proteins, neurophysin 2 anda glycopeptide, copeptin. Arginine vasopressin is a posteriorpituitary hormone which is synthesized in the supraoptic nucleusand paraventricular nucleus of the hypothalamus. Along with itscarrier protein, neurophysin 2, it is packaged into neurosecretoryvesicles and transported axonally to the nerve endings in theneurohypophysis where it is either stored or secreted into thebloodstream. The precursor is thought to be activated while it isbeing transported along the axon to the posterior pituitary.Arginine vasopressin acts as a growth factor by enhancing pHregulation through acid-base transport systems. It has a directantidiuretic action on the kidney, and also causes vasoconstrictionof the peripheral vessels. This hormone can contract smooth muscleduring parturition and lactation. It is also involved in cognition,tolerance, adaptation and complex sexual and maternal behaviour, aswell as in the regulation of water excretion and cardiovascularfunctions.
PubMed ID:http://aac.asm.org/content/53/9/3822.abstract