Product Name: Avian Influenza Nonstructural Protein 1 Antibody
Species Reactivity: Virus
Tested Applications: ELISA
Applications: Avian Influenza Nonstructural Protein 1 antibody can be used for the detection of the avian influenza nonstructural protein 1 protein from influenza A in ELISA.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Avian Influenza Nonstructural Protein 1 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of the Avian Influenza Nonstructural Protein 1 protein.Efforts were made to use relatively conserved regions of the viral sequence as the antigen.The immunogen is located within the last 50 amino acids of Avian Influenza Nonstructural Protein 1.
Host Species: Rabbit
Purification: Avian Influenza Nonstructural Protein 1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1429176-69-1
Product: Mutant IDH1-IN-2
Buffer: Avian Influenza Nonstructural Protein 1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: Avian Influenza Nonstructural Protein 1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Avian Influenza Nonstructural Protein 1 Antibody:
Accession NO.: ABC72653
Protein Ino: 85680915
Official Symbol:
Geneid:
Background: Avian Influenza Nonstructural Protein 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however, it is in birds that all subtypes, including the so-called avian flu or H5N1, can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2-5OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.
PubMed ID:http://aac.asm.org/content/53/8/3447.abstract
