Product Name: ATP2A2 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 115 kDa
Immunogen: This ATP2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the Central region of human ATP2A2.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1345823-20-2
Product: CY5-YNE
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, ATP2A2, ATP2B
Accession NO.: P16615
Protein Ino: 114312
Official Symbol: ATP2A2
Geneid: 488
Background: This gene encodes one of the SERCA Ca(2+)-ATPases, whichare intracellular pumps located in the sarcoplasmic or endoplasmicreticula of muscle cells. This enzyme catalyzes the hydrolysis ofATP coupled with the translocation of calcium from the cytosol intothe sarcoplasmic reticulum lumen, and is involved in regulation ofthe contraction/relaxation cycle. Mutations in this gene causeDarier-White disease, also known as keratosis follicularis, anautosomal dominant skin disorder characterized by loss of adhesionbetween epidermal cells and abnormal keratinization. Alternativesplicing results in multiple transcript variants encoding differentisoforms.
PubMed ID:http://aac.asm.org/content/53/7/3049.abstract
