Product Name: ATP11A Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, ICC, IF, WB
Applications: ATP11A antibody can be used for detection of ATP11A by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: ATP11A antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATP11A.The immunogen is located within the first 50 amino acids of ATP11A.
Host Species: Rabbit
Purification: ATP11A Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1626387-80-1
Product: AZD3759
Buffer: ATP11A Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: ATP11A antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ATP11A Antibody: ATPIH, ATPIS, ATPIH, KIAA1021, Probable phospholipid-transporting ATPase IH, ATPase IS
Accession NO.: NP_115565
Protein Ino: 150421681
Official Symbol: ATP11A
Geneid: 23250
Background: ATP11A Antibody: ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.
PubMed ID:http://aac.asm.org/content/53/7/2965.abstract
