Product Name: ATF2 (phospho Thr69 / 51) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: IF, IHC, WB
Applications: Western Blot: 1:500, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
User Note:
Predicted Molecular Weight: 65 – 75 kDa
Immunogen: ATF2 (Phospho-Thr69 or 51) antibody was raised against a peptide sequence around phosphorylation site of threonine 69 or 51 (D-Q-T (p) -P-T) derived from Human ATF2.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Physical State: Liquid
CAS NO.: 1234708-04-3
Product: hPGDS-IN-1
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: HB16, CREB2, TREB7, CREB-2, CRE-BP1, PKB, RAC, CREBP1
Accession NO.: NP_001871.2
Protein Ino: 22538422
Official Symbol: ATF2
Geneid: 1386
Background: Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
PubMed ID:http://aac.asm.org/content/53/7/2707.abstract
