Product Name: ASCL1 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC, WB
Applications: ASCL1 antibody can be used for detection of ASCL1 by ELISA at 1:312500. ASCL1 antibody can be used for detection of ASCL1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 25 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ASCL1.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 111696-23-2
Product: Cefetamet pivoxil (hydrochloride)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store ASCL1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ASCL1, ASH1, HASH1, MASH1, bHLHa46
Accession NO.: NP_004307
Protein Ino: 55743094
Official Symbol: ASCL1
Geneid: 429
Background: ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5-CANNTG-3). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers.
PubMed ID:http://aac.asm.org/content/53/6/2312.abstract
