Product Name: ASB2 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 65 kDa
Immunogen: This ASB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ASB2.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1276553-09-3
Product: PF-4989216
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.38 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Ankyrin repeat and SOCS box protein 2, ASB-2, ASB2
Accession NO.: Q96Q27
Protein Ino: 20531999
Official Symbol: ASB2
Geneid: 51676
Background: The protein encoded by this gene is a member of theankyrin repeat and SOCS box-containing (ASB) family of proteins.They contain ankyrin repeat sequence and SOCS box domain. The SOCSbox serves to couple suppressor of cytokine signalling (SOCS)proteins and their binding partners with the elongin B and Ccomplex, possibly targeting them for degradation. This gene isinduced by all-trans retinoic acid. In myeloid leukemia cells, theexpression of this encoded protein has been shown to induce growthinhibition and chromatin condensation. Multiple alternativelyspliced transcript variants have been described for this gene buttheir full length sequences are not known.
PubMed ID:http://aac.asm.org/content/53/6/2687.abstract
