Product Name: ARHGEF6 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 87 kDa
Immunogen: This ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 57103-68-1
Product: Maytansinol
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Rho guanine nucleotide exchange factor 6, Alpha-Pix, COOL-2, PAK-interacting exchange factor alpha, Rac/Cdc42 guanine nucleotide exchange factor 6, ARHGEF6, COOL2, KIAA0006, PIXA
Accession NO.: Q15052
Protein Ino: 17371603
Official Symbol: ARHGEF6
Geneid: 9459
Background: Rho GTPases play a fundamental role in numerous cellularprocesses that are initiated by extracellular stimuli that workthrough G protein coupled receptors. The encoded protein belongs toa family of cytoplasmic proteins that activate the Ras-like familyof Rho proteins by exchanging bound GDP for GTP. It may form acomplex with G proteins and stimulate Rho-dependent signals. Thisprotein is activated by PI3-kinase. Mutations in this gene cancause X-chromosomal non-specific mental retardation. [provided byRefSeq].
PubMed ID:http://aac.asm.org/content/53/4/1501.abstract
