Product Name: Apoa5(ab) Antibody [1G5G9(c)]
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: Western Blot, ELISA.Dilution:Western Blot:1:2000 – 1:5,000ELISA:Determining optimal working dilutions by titration test.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Ni-NTA purified recombinant human APOA5 expressed in E. Coli strain BL21 (DE3).
Host Species: Mouse
Purification:
Physical State:
CAS NO.: 393514-24-4
Product: BCTC
Buffer: Purified antibody in PBS containing 0.03% sodium azide.
Concentration:
Storage Conditions: Apoa5(ab) monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: RAP3, UNQ411/PRO773, Apolipoprotein A5, Apo-AV, RAP3, APOAV
Accession NO.: Q6Q788
Protein Ino: 60391728
Official Symbol: APOA5
Geneid: 116519
Background: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.
PubMed ID:http://aac.asm.org/content/53/2/791.abstract
