Product Name: AMACR / p504S Antibody [AMACR/1723]
Species Reactivity: Human
Tested Applications: IF, IHC-P, WB
Applications: Immunohistology (FFPE): 1-2 ug/ml for 30 minutes at RTIF: 1-2 ug/mlOptimal dilution of the AMACR antibody should be determined by the researcher.
User Note: Optimal dilutions for each application to be determined by the researcher
Predicted Molecular Weight:
Immunogen: A recombinant human protein was used as the immunogen for the AMACR antibody.
Host Species: Mouse
Purification: Protein G affinity chromatography
Physical State: Liquid
CAS NO.: 104391-26-6
Product: CGP 25454A
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Conditions: Aliquot and Store at -20C. Avoid freez-thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
Accession NO.:
Protein Ino:
Official Symbol: AMACR
Geneid: 23600
Background: AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
PubMed ID:http://aac.asm.org/content/52/10/3642.abstract
