Product Name: ALOX15B Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: ALOX15B antibody can be used for detection of ALOX15B by ELISA at 1:312500. ALOX15B antibody can be used for detection of ALOX15B by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 74 kDa, 73 kDa, 67 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALOX15B.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 80734-02-7
Product: Lenampicillin (hydrochloride)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store ALOX15B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: ALOX15B, 15-LOX-2
Accession NO.: NP_001132
Protein Ino: 85067501
Official Symbol: ALOX15B
Geneid: 247
Background: ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively.This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
PubMed ID:http://aac.asm.org/content/52/9/3433.abstract