Product Name :
GR 113808
Description:
GR 113808 is a potent and highly selective 5-HT4 receptor antagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors.
CAS:
144625-51-4
Molecular Weight:
393.50
Formula:
C19H27N3O4S
Chemical Name:
[1-(2-methanesulfonamidoethyl)piperidin-4-yl]methyl 1-methyl-1H-indole-3-carboxylate
Smiles :
CN1C=C(C2=CC=CC=C12)C(=O)OCC1CCN(CCNS(C)(=O)=O)CC1
InChiKey:
MOZPSIXKYJUTKI-UHFFFAOYSA-N
InChi :
InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ibezapolstat} web|{Ibezapolstat} Anti-infection|{Ibezapolstat} Technical Information|{Ibezapolstat} In stock|{Ibezapolstat} supplier|{Ibezapolstat} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Ridinilazole} web|{Ridinilazole} Anti-infection|{Ridinilazole} Protocol|{Ridinilazole} In Vitro|{Ridinilazole} supplier|{Ridinilazole} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
GR 113808 is a potent and highly selective 5-HT4 receptor antagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors.|Product information|CAS Number: 144625-51-4|Molecular Weight: 393.PMID:27108903 50|Formula: C19H27N3O4S|Chemical Name: [1-(2-methanesulfonamidoethyl)piperidin-4-yl]methyl 1-methyl-1H-indole-3-carboxylate|Smiles: CN1C=C(C2=CC=CC=C12)C(=O)OCC1CCN(CCNS(C)(=O)=O)CC1|InChiKey: MOZPSIXKYJUTKI-UHFFFAOYSA-N|InChi: InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|GR113808 (intraperitoneal injection; 1 mg/kg; 5-7 days starting 24 h after induction of colitis) shows a significant increase in the disease activity index (DAI),which includes evaluation of weight loss, stool consistency, and presence of fecal blood.|Products are for research use only. Not for human use.|
