Product Name: AKT3 Antibody [66C1247.1]
Species Reactivity: Bat, Bovine, Chicken, Dog, Gibbon, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Tested Applications: IHC, WB
Applications: AKT3 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 – 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 – 1:1000, and flow cytometry starting at 1:200 – 1:400.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: AKT3 monoclonal antibody was raised against amino acids 119 – 136 of AKT3 (Human).
Host Species: Mouse
Purification: Protein G Column
Physical State: Liquid
CAS NO.: 681492-22-8
Product: Delamanid
Buffer: PBS, 0.05% BSA, 0.05% sodium azide.
Concentration:
Storage Conditions: Store AKT3 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: AKT3, AKT3/PKBgamma, PRKBG, PKB gamma, Protein kinase Akt-3, RAC-gamma, MPPH, PKB-GAMMA, PKBG, Protein kinase B gamma, RAC-PK-gamma, STK-2
Accession NO.: Q9Y243
Protein Ino: 12643943
Official Symbol: AKT3
Geneid: 10000
Background: Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity.
PubMed ID:http://aac.asm.org/content/52/8/2937.abstract
