anti-epcam mouse mab

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Recombinant Anti-EpCAM Mouse mAb Clone Number: 10610 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: Ep-CAM, TROP1, EGP, EGP314, hEGP314, KSA, CD326 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2b/kappa Conjugate Unconjugated Synonyms Ep-CAM, TROP1, EGP, EGP314, hEGP314, KSA, CD326 UniProt ID P16422 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, it has oncogenic potential via its capacity to upregulate c-Myc, E-FABP, and Cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, it can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies. Cellular location Membrane Images FC Cell line: HT-29 Fixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat Anti-Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies (Black line).Isotype control: Mouse monoclonal IgG2b (Blue line). Description: Line red is the positive signal for :
Recombinant Anti-EpCAM Mouse mAb Clone Number: 10610 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: Ep-CAM, TROP1, EGP, EGP314, hEGP314, KSA, CD326 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2b/kappa Conjugate Unconjugated Synonyms Ep-CAM, TROP1, EGP, EGP314, hEGP314, KSA, CD326 UniProt ID P16422 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, it has oncogenic potential via its capacity to upregulate c-Myc, E-FABP, and Cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, it can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies. Cellular location Membrane Images FC Cell line: HT-29 Fixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat Anti-Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies (Black line).Isotype control: Mouse monoclonal IgG2b (Blue line). Description: Line red is the positive signal for