Product Name: AKAP4 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC-P, WB
Applications: AKAP4 antibody can be used for detection of AKAP4 by Western blot at 1 – 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 94 kDa Observed: 100 kDa
Immunogen: AKAP4 antibody was raised against a 17 amino acid peptide near the amino terminus of human AKAP4.The immunogen is located within the first 50 amino acids of AKAP4.
Host Species: Rabbit
Purification: AKAP4 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 2012607-27-9
Product: WNK463
Buffer: AKAP4 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: AKAP4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: A-kinase anchor protein 4, AKAP-4, AKAP82, hAKAP82, CT99, FSC1, HI, PRKA4
Accession NO.: NP_003877
Protein Ino: 21493037
Official Symbol: AKAP4
Geneid: 8852
Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell (1). AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm (2). It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways (2). AKAP4 has also been postulated to be a potential biomarker for breast cancer (3).
PubMed ID:http://aac.asm.org/content/52/7/2442.abstract
