Product Name: AJAP1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, ICC, WB
Applications: AJAP1 antibody can be used for detection of AJAP1 by Western blot at 1 – 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 45 kDa Observed: 48 kDa
Immunogen: AJAP1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human AJAP1.The immunogen is located within amino acids 290 – 340 of AJAP1.
Host Species: Rabbit
Purification: AJAP1 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 72957-38-1
Product: Porcine dynorphin A(1-13)
Buffer: AJAP1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: AJAP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Adherens junctions associated protein 1, Membrane protein shrew-1, MOT8, SHREW1
Accession NO.: NP_061324
Protein Ino: 9055278
Official Symbol: AJAP1
Geneid: 55966
Background: The Adherens Junction Associated Protein 1 (AJAP1) plays a key role in cell adhesion and cell migration (1). It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium (1,2). AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation (3). This facilitates the dissolution of adherens junctions with an increase in cell motility (3,4).
PubMed ID:http://aac.asm.org/content/52/7/2632.abstract
