Product Name :
TASP0433864
Description:
TASP0433864 is a selective positive allosteric modulator (PAM) of metabotropic glutamate 2 (mGlu2) receptor with EC50 values of 199 nM and 206 nM against human and rat mGlu2 receptors, respectively. TASP0433864 has antipsychotic activity.
CAS:
1431980-60-7
Molecular Weight:
329.39
Formula:
C18H23N3O3
Chemical Name:
Smiles :
CC1=C(N=C2O[C@H](COC3C=CC(=CC=3)C(C)(C)C)CN12)C(N)=O
InChiKey:
IZYYTLCSQBACIP-AWEZNQCLSA-N
InChi :
InChI=1S/C18H23N3O3/c1-11-15(16(19)22)20-17-21(11)9-14(24-17)10-23-13-7-5-12(6-8-13)18(2,3)4/h5-8,14H,9-10H2,1-4H3,(H2,19,22)/t14-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
TASP0433864 is a selective positive allosteric modulator (PAM) of metabotropic glutamate 2 (mGlu2) receptor with EC50 values of 199 nM and 206 nM against human and rat mGlu2 receptors, respectively. TASP0433864 has antipsychotic activity.|Product information|CAS Number: 1431980-60-7|Molecular Weight: 329.39|Formula: C18H23N3O3|Smiles: CC1=C(N=C2O[C@H](COC3C=CC(=CC=3)C(C)(C)C)CN12)C(N)=O|InChiKey: IZYYTLCSQBACIP-AWEZNQCLSA-N|InChi: InChI=1S/C18H23N3O3/c1-11-15(16(19)22)20-17-21(11)9-14(24-17)10-23-13-7-5-12(6-8-13)18(2,3)4/h5-8,14H,9-10H2,1-4H3,(H2,19,22)/t14-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Caspofungin diacetate} MedChemExpress|{Caspofungin diacetate} Fungal|{Caspofungin diacetate} Epigenetics|{Caspofungin diacetate} Technical Information|{Caspofungin diacetate} Purity|{Caspofungin diacetate} manufacturer} |Shelf Life: ≥12 months if stored properly.{{Linagliptin} MedChemExpress|{Linagliptin} Dipeptidyl Peptidase|{Linagliptin} Protocol|{Linagliptin} In stock|{Linagliptin} manufacturer|{Linagliptin} Cancer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24275718 |Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Hiyoshi T, et al. Neurophysiologic and antipsychotic profiles of TASP0433864, a novel positive allosteric modulator of metabotropic glutamate 2 receptor. J Pharmacol Exp Ther. 2014 Dec;351(3):642-53.Products are for research use only. Not for human use.|
