Product Name :
Mcl1-IN-12
Description:
Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity.
CAS:
2042211-12-9
Molecular Weight:
803.00
Formula:
C45H46N4O6S2
Chemical Name:
N-{4-[(3-nitro-4-{[2-(phenylsulfanyl)ethyl]amino}benzenesulfonyl)carbamoyl]phenyl}-4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzamide
Smiles :
CC1=CC2=C(C=C1C(=C)C1C=CC(=CC=1)C(=O)NC1C=CC(=CC=1)C(=O)NS(=O)(=O)C1=CC(=C(C=C1)NCCSC1C=CC=CC=1)[N+]([O-])=O)C(C)(C)CCC2(C)C
InChiKey:
PVBCFXWUROOQLS-UHFFFAOYSA-N
InChi :
InChI=1S/C45H46N4O6S2/c1-29-26-38-39(45(5,6)23-22-44(38,3)4)28-37(29)30(2)31-12-14-32(15-13-31)42(50)47-34-18-16-33(17-19-34)43(51)48-57(54,55)36-20-21-40(41(27-36)49(52)53)46-24-25-56-35-10-8-7-9-11-35/h7-21,26-28,46H,2,22-25H2,1,3-6H3,(H,47,50)(H,48,51)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Dolutegravir} web|{Dolutegravir} HIV|{Dolutegravir} Purity & Documentation|{Dolutegravir} In stock|{Dolutegravir} supplier|{Dolutegravir} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Zafirlukast} site|{Zafirlukast} GPCR/G Protein|{Zafirlukast} Biological Activity|{Zafirlukast} In Vivo|{Zafirlukast} custom synthesis|{Zafirlukast} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24360118
Additional information:
Mcl1-IN-12 (Compound F) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively. Anti-tumor activity.|Product information|CAS Number: 2042211-12-9|Molecular Weight: 803.00|Formula: C45H46N4O6S2|Chemical Name: N-{4-[(3-nitro-4-{[2-(phenylsulfanyl)ethyl]amino}benzenesulfonyl)carbamoyl]phenyl}-4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzamide|Smiles: CC1=CC2=C(C=C1C(=C)C1C=CC(=CC=1)C(=O)NC1C=CC(=CC=1)C(=O)NS(=O)(=O)C1=CC(=C(C=C1)NCCSC1C=CC=CC=1)[N+]([O-])=O)C(C)(C)CCC2(C)C|InChiKey: PVBCFXWUROOQLS-UHFFFAOYSA-N|InChi: InChI=1S/C45H46N4O6S2/c1-29-26-38-39(45(5,6)23-22-44(38,3)4)28-37(29)30(2)31-12-14-32(15-13-31)42(50)47-34-18-16-33(17-19-34)43(51)48-57(54,55)36-20-21-40(41(27-36)49(52)53)46-24-25-56-35-10-8-7-9-11-35/h7-21,26-28,46H,2,22-25H2,1,3-6H3,(H,47,50)(H,48,51)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
