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Product Name :
anti-cd47 rabbit mab

Isotype :
IgG

Conjugate :
Unconjugated

Synonyms:
MER6, IAP

UniProt ID :
Q08722

Immunogen:

MW (kDa) :

Specificity:

Purity :
Protein A purified

Purity :
PBS, Glycerol, BSA

Storage :
Store at -20°C. Avoid freeze/thaw cycles.

Stability:
Stable for 12 months from date of receipt/reconstitution.

Background :
CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 plays an important role in memory formation and synaptic plasticity in the hippocampus. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 interacts with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. CD47 may prevent premature elimination of red blood cells. CD47 may be involved in membrane permeability changes induced following virus infection. Cellular location Cell membrane

Images :
WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1: 2000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgGH&L (HRP Conjugate) Lysate: 1: HepG2(Negative); 2: Jurkat; 3: 293T; 4: A549; 5: U-2 OS; 6: Molt4; 7: HL-60 Protein loading amount: 20 μg Exposure time: 30 secondsPredicted band size: 47-52 kDa Observed band size: 47-52 kDa

Vapor Pressure :
Recombinant Rabbit Monoclonal Anti-CD47 Rabbit mAb Clone Number: JRMR-10320-70B Host: Rabbit Clonality: Recombinant Monoclonal Applications: WB Reactivity: Human Synonyms: MER6, IAP Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms MER6, IAP UniProt ID Q08722 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:1000 – 1:2000 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 plays an important role in memory formation and synaptic plasticity in the hippocampus. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 interacts with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. CD47 may prevent premature elimination of red blood cells. CD47 may be involved in membrane permeability changes induced following virus infection. Cellular location Cell membrane Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1: 2000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgGH&L (HRP Conjugate) Lysate: 1: HepG2(Negative); 2: Jurkat; 3: 293T; 4: A549; 5: U-2 OS; 6: Molt4; 7: HL-60 Protein loading amount: 20 μg Exposure time: 30 secondsPredicted band size: 47-52 kDa Observed band size: 47-52 kDa :

Recombinant Rabbit Monoclonal Anti-CD47 Rabbit mAb Clone Number: JRMR-10320-70B Host: Rabbit Clonality: Recombinant Monoclonal Applications: WB Reactivity: Human Synonyms: MER6, IAP Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms MER6, IAP UniProt ID Q08722 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:1000 – 1:2000 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. CD47 plays an important role in memory formation and synaptic plasticity in the hippocampus. CD47 is a receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 interacts with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. CD47 may prevent premature elimination of red blood cells. CD47 may be involved in membrane permeability changes induced following virus infection. Cellular location Cell membrane Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1: 2000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgGH&L (HRP Conjugate) Lysate: 1: HepG2(Negative); 2: Jurkat; 3: 293T; 4: A549; 5: U-2 OS; 6: Molt4; 7: HL-60 Protein loading amount: 20 μg Exposure time: 30 secondsPredicted band size: 47-52 kDa Observed band size: 47-52 kDa

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Betaine hydrochloride