Product Name :
anti-cd45 mouse mab
Isotype :
IgG1/kappa
Conjugate :
Unconjugated
Synonyms:
L-CA, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200
UniProt ID :
P08575
Immunogen:
MW (kDa) :
Specificity:
Purity :
Protein G purified
Purity :
PBS, Glycerol, BSA
Storage :
Store at -20°C. Avoid freeze/thaw cycles.
Stability:
Stable for 12 months from date of receipt/reconstitution.
Background :
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. Cellular location Membrane
Images :
IHC-P Tissue: Human colon cancerSection type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100Primary incubation condition: 1 hour at room temperatureCounter stain: HematoxylinDescription: The brown color represents the positive signal observed with
Vapor Pressure :
Recombinant Anti-CD45 Mouse mAb Clone Number: 10199 Host: Mouse Clonality: Recombinant Monoclonal Applications: IHC-P ICC/IF FC Reactivity: Human Synonyms: L-CA, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms L-CA, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200 UniProt ID P08575 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species IHC-P 1:50 – 1:100 Human ICC/IF 1:50 – 1:100 Human FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. Cellular location Membrane Images IHC-P Tissue: Human colon cancerSection type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100Primary incubation condition: 1 hour at room temperatureCounter stain: HematoxylinDescription: The brown color represents the positive signal observed with
Recombinant Anti-CD45 Mouse mAb Clone Number: 10199 Host: Mouse Clonality: Recombinant Monoclonal Applications: IHC-P ICC/IF FC Reactivity: Human Synonyms: L-CA, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms L-CA, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200 UniProt ID P08575 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species IHC-P 1:50 – 1:100 Human ICC/IF 1:50 – 1:100 Human FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. Cellular location Membrane Images IHC-P Tissue: Human colon cancerSection type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100Primary incubation condition: 1 hour at room temperatureCounter stain: HematoxylinDescription: The brown color represents the positive signal observed with
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