Share this post on:

Product Name :
anti-cd40 ligand mouse mab

Isotype :
IgG1/kappa

Conjugate :
Unconjugated

Synonyms:
CD40LG, CD40L, TNFSF5, TRAP, CD154

UniProt ID :
P29965

Immunogen:

MW (kDa) :

Specificity:

Purity :
Protein G purified

Purity :
PBS, Glycerol, BSA

Storage :
Store at -20°C. Avoid freeze/thaw cycles.

Stability:
Stable for 12 months from date of receipt/reconstitution.

Background :
Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. Cellular location Membrane, Secreted

Images :
FC Specimen: PBMCFixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies(Black line).Isotype control: Mouse monoclonal IgG1 (Blue line). Description: Line red is the positive signal for

Vapor Pressure :
Recombinant Anti-CD40 Ligand Mouse mAb Clone Number: 12104 Host: Mouse Clonality: Recombinant Monoclonal Applications: FC Reactivity: Human Synonyms: CD40LG, CD40L, TNFSF5, TRAP, CD154 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms CD40LG, CD40L, TNFSF5, TRAP, CD154 UniProt ID P29965 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. Cellular location Membrane, Secreted Images FC Specimen: PBMCFixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies(Black line).Isotype control: Mouse monoclonal IgG1 (Blue line). Description: Line red is the positive signal for :

Recombinant Anti-CD40 Ligand Mouse mAb Clone Number: 12104 Host: Mouse Clonality: Recombinant Monoclonal Applications: FC Reactivity: Human Synonyms: CD40LG, CD40L, TNFSF5, TRAP, CD154 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms CD40LG, CD40L, TNFSF5, TRAP, CD154 UniProt ID P29965 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. Cellular location Membrane, Secreted Images FC Specimen: PBMCFixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies(Black line).Isotype control: Mouse monoclonal IgG1 (Blue line). Description: Line red is the positive signal for

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Myosin light chain kinase Rabbit mAb In Vitro
SOD2 (Y20P09) Mouse mAb Purity & Documentation
CDK1 Antibody: CDK1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 34 kDa, targeting to CDK1. It can be used for WB,IP assays with tag free, in the background of Human.

Share this post on:

Author: Betaine hydrochloride