Product Name :
anti-cd40 ligand mouse mab
Isotype :
IgG1/kappa
Conjugate :
Unconjugated
Synonyms:
CD40LG, CD40L, TNFSF5, TRAP, CD154
UniProt ID :
P29965
Immunogen:
MW (kDa) :
Specificity:
Purity :
Protein G purified
Purity :
PBS, Glycerol, BSA
Storage :
Store at -20°C. Avoid freeze/thaw cycles.
Stability:
Stable for 12 months from date of receipt/reconstitution.
Background :
Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. Cellular location Membrane, Secreted
Images :
FC Specimen: PBMCFixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies(Black line).Isotype control: Mouse monoclonal IgG1 (Blue line). Description: Line red is the positive signal for
Vapor Pressure :
Recombinant Anti-CD40 Ligand Mouse mAb Clone Number: 12104 Host: Mouse Clonality: Recombinant Monoclonal Applications: FC Reactivity: Human Synonyms: CD40LG, CD40L, TNFSF5, TRAP, CD154 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms CD40LG, CD40L, TNFSF5, TRAP, CD154 UniProt ID P29965 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. Cellular location Membrane, Secreted Images FC Specimen: PBMCFixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies(Black line).Isotype control: Mouse monoclonal IgG1 (Blue line). Description: Line red is the positive signal for
Recombinant Anti-CD40 Ligand Mouse mAb Clone Number: 12104 Host: Mouse Clonality: Recombinant Monoclonal Applications: FC Reactivity: Human Synonyms: CD40LG, CD40L, TNFSF5, TRAP, CD154 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms CD40LG, CD40L, TNFSF5, TRAP, CD154 UniProt ID P29965 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. Cellular location Membrane, Secreted Images FC Specimen: PBMCFixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies(Black line).Isotype control: Mouse monoclonal IgG1 (Blue line). Description: Line red is the positive signal for
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