anti-cd4 mouse mab

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Recombinant Anti-CD4 Mouse mAb Clone Number: 12748 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: T-cell surface antigen T4/Leu-3 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms T-cell surface antigen T4/Leu-3 UniProt ID P01730 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK- Cellular location Membrane Images FC Cell line: PBMCsFixative: UnfixedPermeabilization: NonePrimary Ab dilution: 1:50Primary incubation condition: 1 hour at room temperatureNuclear counter stain: DAPI (Blue)Description: The green color represents the positive signal observed with :
Recombinant Anti-CD4 Mouse mAb Clone Number: 12748 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: T-cell surface antigen T4/Leu-3 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG1/kappa Conjugate Unconjugated Synonyms T-cell surface antigen T4/Leu-3 UniProt ID P01730 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK- Cellular location Membrane Images FC Cell line: PBMCsFixative: UnfixedPermeabilization: NonePrimary Ab dilution: 1:50Primary incubation condition: 1 hour at room temperatureNuclear counter stain: DAPI (Blue)Description: The green color represents the positive signal observed with