Product Name: AGPAT2 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: AGPAT2 antibody can be used for detection of AGPAT2 by ELISA at 1:312500. AGPAT2 antibody can be used for detection of AGPAT2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 27 kDa, 31 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AGPAT2.
Host Species: Rabbit
Purification: Antibody is purified by protein A chromatography method.
Physical State: Lyophilized
CAS NO.: 1642300-78-4
Product: KPT-8602 (Z-isomer)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store AGPAT2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: AGPAT2, 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
Accession NO.: NP_001012745
Protein Ino: 69122971
Official Symbol: AGPAT2
Geneid: 10555
Background: AGPAT2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance.This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
PubMed ID:http://aac.asm.org/content/52/6/2149.abstract
